Comparison of the non-nucleoside reverse transcriptase inhibitor lersivirine with its pyrazole and imidazole isomers.

Jones, Lyn H

Comparison of the non-nucleoside reverse transcriptase inhibitor lersivirine with its pyrazole and imidazole isomers. [electronic resource] - Chemical biology & drug design May 2011 - 393-7 p. digital

Publication Type: Letter

1747-0285

10.1111/j.1747-0285.2011.01113.x doi


Animals
Drug Design
HIV Infections--drug therapy
HIV Reverse Transcriptase--antagonists & inhibitors
HIV-1--drug effects
Humans
Imidazoles--chemistry
Microsomes, Liver--drug effects
Models, Molecular
Mutation
Nitriles--chemistry
Pyrazoles--chemistry
Rats
Reverse Transcriptase Inhibitors--chemistry
Structure-Activity Relationship