Differential response of human and mouse dendritic cells to VEGF determines interspecies discrepancies in tumor-mediated TH1/TH2 polarity shift.

Block, Matthew S

Differential response of human and mouse dendritic cells to VEGF determines interspecies discrepancies in tumor-mediated TH1/TH2 polarity shift. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Apr 2011 - 1776-83 p. digital

Publication Type: Comparative Study; Journal Article

1557-3265

10.1158/1078-0432.CCR-10-2836 doi


Animals
Cell Line, Tumor
Dendritic Cells--drug effects
Female
Gene Expression Regulation, Neoplastic
Granulocyte-Macrophage Colony-Stimulating Factor--blood
Humans
Interleukin-12 Subunit p40--genetics
Interleukin-4--genetics
Interleukins--blood
Mammary Neoplasms, Experimental--immunology
Melanoma, Experimental--immunology
Mice
Mice, Inbred C57BL
Neoplasm Transplantation
Receptors, Vascular Endothelial Growth Factor--metabolism
Species Specificity
Spleen--cytology
Th1 Cells--drug effects
Th2 Cells--drug effects
Transcription, Genetic
Transplantation, Heterologous
Vascular Endothelial Growth Factor A--blood