Collagen I regulates the self-renewal of mouse embryonic stem cells through α2β1 integrin- and DDR1-dependent Bmi-1.

Suh, Han Na

Collagen I regulates the self-renewal of mouse embryonic stem cells through α2β1 integrin- and DDR1-dependent Bmi-1. [electronic resource] - Journal of cellular physiology Dec 2011 - 3422-32 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-4652

10.1002/jcp.22697 doi


Animals
Cell Adhesion
Cell Cycle Proteins--metabolism
Cell Line
Cell Proliferation
Collagen Type I--metabolism
Discoidin Domain Receptor 1
Embryonic Stem Cells--enzymology
Extracellular Signal-Regulated MAP Kinases--metabolism
Gene Expression Regulation, Developmental
Integrin alpha2beta1--metabolism
Kruppel-Like Transcription Factors--metabolism
Mice
Nuclear Proteins--genetics
Phosphatidylinositol 3-Kinase--metabolism
Phosphorylation
Pluripotent Stem Cells--enzymology
Polycomb Repressive Complex 1
Protein Serine-Threonine Kinases--metabolism
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins c-akt--metabolism
RNA Interference
RNA, Messenger--metabolism
Receptor Protein-Tyrosine Kinases--metabolism
Receptors, Notch--metabolism
Repressor Proteins--genetics
Signal Transduction--genetics
Time Factors
Zinc Finger Protein GLI1
ras Proteins--metabolism