Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors.

Tian, Ya-Min

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors. [electronic resource] - The Journal of biological chemistry Apr 2011 - 13041-51 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M110.211110 doi


Animals
Cell Hypoxia--physiology
Drosophila melanogaster
Enzyme Inhibitors--pharmacology
Hep G2 Cells
Humans
Hydroxylation--physiology
Hypoxia-Inducible Factor 1, alpha Subunit--genetics
K562 Cells
Male
Oxygenases--antagonists & inhibitors
Protein Structure, Tertiary--physiology
Rats
Rats, Sprague-Dawley
Ubiquitin-Protein Ligases--genetics
p300-CBP Transcription Factors