Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome.

Yazawa, Masayuki

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome. [electronic resource] - Nature Mar 2011 - 230-4 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1476-4687

10.1038/nature09855 doi


Action Potentials--drug effects
Autistic Disorder
Calcium Channels, L-Type--genetics
Calcium Signaling--drug effects
Cell Transdifferentiation
Cellular Reprogramming--genetics
Drug Evaluation, Preclinical--methods
Fibroblasts--cytology
HEK293 Cells
Humans
Induced Pluripotent Stem Cells--pathology
Long QT Syndrome--drug therapy
Mutation, Missense--genetics
Myocytes, Cardiac--drug effects
Patch-Clamp Techniques
Phenotype
Purines--pharmacology
Roscovitine
Single-Cell Analysis
Syndactyly--drug therapy