The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression.

Chan, Peter

The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression. [electronic resource] - Breast cancer research : BCR Feb 2011 - R19 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1465-542X

10.1186/bcr2828 doi


Adult
Aged
Aged, 80 and over
Breast Neoplasms--genetics
Cohort Studies
DNA Methylation
Female
Gene Dosage
Gene Expression
Humans
Kaplan-Meier Estimate
Mammary Glands, Human--metabolism
Middle Aged
Neoplasm Staging
Nuclear Proteins--genetics
Phenotype
Promoter Regions, Genetic
Tumor Suppressor Protein p53--metabolism
Ubiquitin-Protein Ligases--genetics
Young Adult
Seven in Absentia Proteins