Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation.
Thomas, Bobby
Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation. [electronic resource] - PloS one Jan 2011 - e16706 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0016706 doi
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine--pharmacology
Animals
Cell Survival
Dopamine Agents--pharmacology
Enzyme Activation
Humans
MPTP Poisoning--prevention & control
Mice
Mice, Knockout
Neurotoxicity Syndromes--etiology
Neurotoxins--pharmacology
Oncogene Protein v-akt--metabolism
alpha-Synuclein--deficiency
beta-Synuclein--physiology
Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation. [electronic resource] - PloS one Jan 2011 - e16706 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1932-6203
10.1371/journal.pone.0016706 doi
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine--pharmacology
Animals
Cell Survival
Dopamine Agents--pharmacology
Enzyme Activation
Humans
MPTP Poisoning--prevention & control
Mice
Mice, Knockout
Neurotoxicity Syndromes--etiology
Neurotoxins--pharmacology
Oncogene Protein v-akt--metabolism
alpha-Synuclein--deficiency
beta-Synuclein--physiology