A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis.

Wallis, Susan K

A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis. [electronic resource] - Arthritis research & therapy Feb 2011 - R15 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1478-6362

10.1186/ar3239 doi


Adult
Arthritis, Rheumatoid--genetics
Cell Separation
Cells, Cultured
Cross-Sectional Studies
Female
Genetic Predisposition to Disease--genetics
Genotype
Humans
Interleukin-17--biosynthesis
Interleukin-4--immunology
Male
Middle Aged
Pilot Projects
Polymorphism, Single Nucleotide
Receptors, Interleukin-4--genetics
Signal Transduction--genetics
Th17 Cells--immunology
Young Adult