Modular bioreactor for primary human hepatocyte culture: medium flow stimulates expression and activity of detoxification genes.

Vinci, Bruna

Modular bioreactor for primary human hepatocyte culture: medium flow stimulates expression and activity of detoxification genes. [electronic resource] - Biotechnology journal May 2011 - 554-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1860-7314

10.1002/biot.201000326 doi


ATP Binding Cassette Transporter, Subfamily B--genetics
ATP Binding Cassette Transporter, Subfamily B, Member 1--genetics
Aryl Hydrocarbon Hydroxylases--genetics
Bioreactors
Cells, Cultured
Cytochrome P-450 CYP1A1--genetics
Cytochrome P-450 CYP1A2--genetics
Cytochrome P-450 CYP2B6
Glucuronosyltransferase--genetics
Glutathione Transferase--genetics
Hepatocytes--cytology
Humans
Oxidoreductases, N-Demethylating--genetics
Reverse Transcriptase Polymerase Chain Reaction
Shear Strength
ATP-Binding Cassette Sub-Family B Member 4