Recognition of cytoplasmic RNA results in cathepsin-dependent inflammasome activation and apoptosis in human macrophages.

Rintahaka, Johanna

Recognition of cytoplasmic RNA results in cathepsin-dependent inflammasome activation and apoptosis in human macrophages. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Mar 2011 - 3085-92 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1550-6606

10.4049/jimmunol.1002051 doi


Apoptosis--genetics
Cathepsins--antagonists & inhibitors
Cells, Cultured
Cytoplasm--genetics
Encephalomyocarditis virus--immunology
Humans
Inflammasomes--immunology
Macrophages--enzymology
Molecular Mimicry--immunology
Poly I-C--immunology
RNA, Double-Stranded--immunology
RNA, Viral--immunology
Signal Transduction--immunology
Vesicular stomatitis Indiana virus--immunology