Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells.

Hsu, Han-Shui

Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells. [electronic resource] - Cancer Jul 2011 - 2970-85 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-0142

10.1002/cncr.25869 doi


AC133 Antigen
Aged
Animals
Antigens, CD--analysis
Apoptosis--drug effects
Blotting, Western
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Proliferation
Cell Separation
Drug Resistance, Neoplasm
Enzyme-Linked Immunosorbent Assay
Female
Fluorescent Antibody Technique
Glycoproteins--analysis
Homeodomain Proteins--biosynthesis
Humans
Lung Neoplasms--drug therapy
Male
Mice
Middle Aged
Nanog Homeobox Protein
Neoplasm Metastasis
Neoplasm Transplantation
Neoplastic Stem Cells--drug effects
Octamer Transcription Factor-3--biosynthesis
Peptides--analysis
Proto-Oncogene Proteins c-bcl-2--genetics
Radiation Tolerance
SOXB1 Transcription Factors--biosynthesis
STAT3 Transcription Factor--antagonists & inhibitors
Signal Transduction--drug effects
Triterpenes--pharmacology
Tumor Cells, Cultured
bcl-X Protein--genetics