Phase I studies of CBP501, a G2 checkpoint abrogator, as monotherapy and in combination with cisplatin in patients with advanced solid tumors.
Shapiro, Geoffrey I
Phase I studies of CBP501, a G2 checkpoint abrogator, as monotherapy and in combination with cisplatin in patients with advanced solid tumors. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research May 2011 - 3431-42 p. digital
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
1557-3265
10.1158/1078-0432.CCR-10-2345 doi
Adult
Aged
Aged, 80 and over
Antineoplastic Agents--administration & dosage
Antineoplastic Combined Chemotherapy Protocols--adverse effects
Cisplatin--administration & dosage
Disease Progression
Female
G2 Phase--drug effects
Genes, cdc--drug effects
Humans
Male
Maximum Tolerated Dose
Middle Aged
Neoplasms--drug therapy
Peptide Fragments--administration & dosage
cdc25 Phosphatases--administration & dosage
Phase I studies of CBP501, a G2 checkpoint abrogator, as monotherapy and in combination with cisplatin in patients with advanced solid tumors. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research May 2011 - 3431-42 p. digital
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
1557-3265
10.1158/1078-0432.CCR-10-2345 doi
Adult
Aged
Aged, 80 and over
Antineoplastic Agents--administration & dosage
Antineoplastic Combined Chemotherapy Protocols--adverse effects
Cisplatin--administration & dosage
Disease Progression
Female
G2 Phase--drug effects
Genes, cdc--drug effects
Humans
Male
Maximum Tolerated Dose
Middle Aged
Neoplasms--drug therapy
Peptide Fragments--administration & dosage
cdc25 Phosphatases--administration & dosage