H1521, a novel derivative of 4-hydroxyquinoline-3-carboxamide, suppresses the development of lupus in mice by inducing Th1 cytokine profile in T cells.

Xiao, Zhi-yong

H1521, a novel derivative of 4-hydroxyquinoline-3-carboxamide, suppresses the development of lupus in mice by inducing Th1 cytokine profile in T cells. [electronic resource] - International immunopharmacology Apr 2011 - 435-43 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1878-1705

10.1016/j.intimp.2010.12.011 doi


Adjuvants, Immunologic--chemistry
Animals
Chronic Disease
Cytokines--biosynthesis
Disease Models, Animal
Female
Graft vs Host Disease--drug therapy
Hydroxyquinolines--chemistry
Lupus Erythematosus, Systemic--immunology
Mice
Mice, Inbred Strains
Th1 Cells--drug effects
Th2 Cells--drug effects