Bax activation by engagement with, then release from, the BH3 binding site of Bcl-xL.

Gautier, F

Bax activation by engagement with, then release from, the BH3 binding site of Bcl-xL. [electronic resource] - Molecular and cellular biology Feb 2011 - 832-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1098-5549

10.1128/MCB.00161-10 doi


Amino Acid Sequence
Animals
Apoptosis Regulatory Proteins--genetics
Binding Sites
Biphenyl Compounds--pharmacology
Cell Death--drug effects
Cell Line, Tumor
Cell-Free System
Cells, Cultured
Gene Knockdown Techniques
HeLa Cells
Humans
In Vitro Techniques
Mice
Mice, Knockout
Mitochondria--metabolism
Models, Biological
Molecular Mimicry
Molecular Sequence Data
Mutation
Nitrophenols--pharmacology
Piperazines--pharmacology
Proto-Oncogene Proteins--genetics
RNA, Small Interfering--genetics
Recombinant Proteins--genetics
Saccharomyces cerevisiae--drug effects
Sulfonamides--pharmacology
Terphenyl Compounds--pharmacology
Tumor Suppressor Proteins--genetics
Two-Hybrid System Techniques
bcl-2-Associated X Protein--deficiency
bcl-X Protein--deficiency