In vivo inhibition of l-buthionine-(S,R)-sulfoximine-induced cataracts by a novel antioxidant, N-acetylcysteine amide.

Carey, Joshua W

In vivo inhibition of l-buthionine-(S,R)-sulfoximine-induced cataracts by a novel antioxidant, N-acetylcysteine amide. [electronic resource] - Free radical biology & medicine Mar 2011 - 722-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1873-4596

10.1016/j.freeradbiomed.2010.12.017 doi


Acetylcysteine--analogs & derivatives
Animals
Antioxidants--pharmacology
Buthionine Sulfoximine
Catalase--metabolism
Cataract--chemically induced
Female
Glutathione--metabolism
Glutathione Peroxidase--metabolism
Glutathione Reductase--metabolism
Lens, Crystalline--drug effects
Male
Malondialdehyde--metabolism
Oxidative Stress--drug effects
Protein Carbonylation--drug effects
Rats
Rats, Wistar