Tissue Factor/ FVIIa prevents the extrinsic pathway of apoptosis by regulation of the tumor suppressor Death-Associated Protein Kinase 1 (DAPK1).

Aberg, M

Tissue Factor/ FVIIa prevents the extrinsic pathway of apoptosis by regulation of the tumor suppressor Death-Associated Protein Kinase 1 (DAPK1). [electronic resource] - Thrombosis research Feb 2011 - 141-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-2472

10.1016/j.thromres.2010.11.015 doi


Apoptosis--drug effects
Apoptosis Regulatory Proteins--biosynthesis
Breast Neoplasms--genetics
Calcium-Calmodulin-Dependent Protein Kinases--biosynthesis
Caspase 8--metabolism
Caspase Inhibitors
Cell Line, Tumor
Death-Associated Protein Kinases
Enzyme Activation
Factor VIIa--genetics
Factor Xa--pharmacology
Fas-Associated Death Domain Protein--metabolism
Female
Humans
Male
Phosphatidylinositol 3-Kinases--metabolism
Phosphorylation
Prostatic Neoplasms--genetics
Proto-Oncogene Proteins c-akt--metabolism
RNA, Messenger--genetics
Receptor, PAR-1--biosynthesis
Receptor, PAR-2--biosynthesis
Recombinant Proteins--pharmacology
Signal Transduction
Thromboplastin--biosynthesis