Prenatal androgenization of female mice programs an increase in firing activity of gonadotropin-releasing hormone (GnRH) neurons that is reversed by metformin treatment in adulthood.

Roland, Alison V

Prenatal androgenization of female mice programs an increase in firing activity of gonadotropin-releasing hormone (GnRH) neurons that is reversed by metformin treatment in adulthood. [electronic resource] - Endocrinology Feb 2011 - 618-28 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1945-7170

10.1210/en.2010-0823 doi


Animals
Dihydrotestosterone--pharmacology
Electrophysiology
Estrous Cycle--drug effects
Female
Glucose Tolerance Test
Gonadotropin-Releasing Hormone--metabolism
Metformin--pharmacology
Mice
Mice, Transgenic
Neurons--drug effects
Pregnancy
Prenatal Exposure Delayed Effects