Triphenylphosphine oxide is a potent and selective inhibitor of the transient receptor potential melastatin-5 ion channel.

Palmer, R Kyle

Triphenylphosphine oxide is a potent and selective inhibitor of the transient receptor potential melastatin-5 ion channel. [electronic resource] - Assay and drug development technologies Dec 2010 - 703-13 p. digital

Publication Type: Journal Article

1557-8127

10.1089/adt.2010.0334 doi


Animals
Calcium--metabolism
HEK293 Cells
Humans
Ion Channel Gating--drug effects
Luminescent Measurements
Membrane Potentials--drug effects
Mice
Mice, Transgenic
Organophosphorus Compounds--chemistry
Patch-Clamp Techniques
Structure-Activity Relationship
TRPM Cation Channels--antagonists & inhibitors
Taste
Taste Buds--drug effects