Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts.

Trimmer, Casey

Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts. [electronic resource] - Cancer biology & therapy Feb 2011 - 383-94 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1555-8576

10.4161/cbt.11.4.14101 doi


Animals
Caveolin 1--genetics
Cell Line, Transformed
Cell Line, Tumor
Cell Proliferation--drug effects
Female
Fibroblasts--drug effects
Gene Expression Regulation, Neoplastic--genetics
Gene Knockdown Techniques
Humans
Mice
Mice, Nude
Mitochondria--enzymology
Models, Biological
Neoplasms--genetics
Nitric Oxide Synthase Type III--genetics
Oxidative Stress--drug effects
Proteomics
RNA, Small Interfering
Recombinant Proteins--genetics
Superoxide Dismutase--genetics
Tumor Microenvironment--drug effects
Xenograft Model Antitumor Assays