Low-dose oral immunization with lyophilized tissue of herbicide-resistant lettuce expressing hepatitis B surface antigen for prototype plant-derived vaccine tablet formulation.

Pniewski, Tomasz

Low-dose oral immunization with lyophilized tissue of herbicide-resistant lettuce expressing hepatitis B surface antigen for prototype plant-derived vaccine tablet formulation. [electronic resource] - Journal of applied genetics May 2011 - 125-36 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2190-3883

10.1007/s13353-010-0001-5 doi


Administration, Oral
Aminobutyrates--pharmacology
Animals
Dose-Response Relationship, Immunologic
Endoplasmic Reticulum--ultrastructure
Feces--chemistry
Freeze Drying
Hepatitis B--prevention & control
Hepatitis B Surface Antigens--biosynthesis
Hepatitis B Vaccines--administration & dosage
Hepatitis B virus--immunology
Herbicide Resistance
Herbicides--pharmacology
Humans
Immunity, Humoral
Immunoglobulin A, Secretory--blood
Lactuca--genetics
Mice
Mice, Inbred BALB C
Plant Leaves--immunology
Plants, Genetically Modified--immunology
Recombinant Proteins--biosynthesis
Vaccination
Vaccines, Edible--administration & dosage