Epidermal growth factor inhibits transcription of type I collagen genes and production of type I collagen in cultured human skin fibroblasts in the presence and absence of L-ascorbic acid 2-phosphate, a long-acting vitamin C derivative.

Kurata, S

Epidermal growth factor inhibits transcription of type I collagen genes and production of type I collagen in cultured human skin fibroblasts in the presence and absence of L-ascorbic acid 2-phosphate, a long-acting vitamin C derivative. [electronic resource] - The Journal of biological chemistry May 1991 - 9997-10003 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258


Ascorbic Acid--analogs & derivatives
Cells, Cultured
Collagen--biosynthesis
DNA--analysis
Electrophoresis, Polyacrylamide Gel
Epidermal Growth Factor--pharmacology
Fibroblasts--drug effects
Humans
Nucleic Acid Hybridization
RNA, Messenger--genetics
Skin--drug effects
Transcription, Genetic--drug effects