Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.

Vicent, Silvestre

Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models. [electronic resource] - The Journal of clinical investigation Nov 2010 - 3940-52 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1558-8238

10.1172/JCI44165 doi


Animals
Cell Line, Tumor
Cell Proliferation
Cell Transformation, Neoplastic
Cellular Senescence--genetics
Fibroblasts--cytology
Gene Expression Profiling
Humans
Lung Neoplasms--genetics
Mice
Proto-Oncogene Proteins--genetics
Proto-Oncogene Proteins p21(ras)--genetics
RNA Interference
Signal Transduction--physiology
WT1 Proteins--genetics
ras Proteins--genetics