Novel HTS strategy identifies TRAIL-sensitizing compounds acting specifically through the caspase-8 apoptotic axis.

Finlay, Darren

Novel HTS strategy identifies TRAIL-sensitizing compounds acting specifically through the caspase-8 apoptotic axis. [electronic resource] - PloS one Oct 2010 - e13375 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1932-6203

10.1371/journal.pone.0013375 doi


Apoptosis
Caspase 8--genetics
Cell Line, Tumor
Humans
Point Mutation
TNF-Related Apoptosis-Inducing Ligand--drug effects