Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition.
Tuffy, Liam P
Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition. [electronic resource] - Molecular and cellular biology Dec 2010 - 5484-501 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1098-5549
10.1128/MCB.00575-10 doi
Animals
Apoptosis--drug effects
Apoptosis Regulatory Proteins--deficiency
Autophagy
BH3 Interacting Domain Death Agonist Protein--deficiency
Base Sequence
Bcl-2-Like Protein 11
Caspase 3--metabolism
Cathepsins--metabolism
Cytochromes c--metabolism
DNA Primers--genetics
Fluorescence Resonance Energy Transfer
Gene Expression
Lysosomes--drug effects
Membrane Potential, Mitochondrial
Membrane Proteins--deficiency
Mice
Mice, Inbred C57BL
Mice, Knockout
Models, Neurological
Nerve Degeneration--genetics
Neurons--cytology
Protease Inhibitors--pharmacology
Proteasome Inhibitors
Proto-Oncogene Proteins--deficiency
Proto-Oncogene Proteins c-bcl-2--genetics
RNA, Small Interfering--genetics
Stress, Physiological
Tumor Suppressor Proteins--deficiency
Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition. [electronic resource] - Molecular and cellular biology Dec 2010 - 5484-501 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1098-5549
10.1128/MCB.00575-10 doi
Animals
Apoptosis--drug effects
Apoptosis Regulatory Proteins--deficiency
Autophagy
BH3 Interacting Domain Death Agonist Protein--deficiency
Base Sequence
Bcl-2-Like Protein 11
Caspase 3--metabolism
Cathepsins--metabolism
Cytochromes c--metabolism
DNA Primers--genetics
Fluorescence Resonance Energy Transfer
Gene Expression
Lysosomes--drug effects
Membrane Potential, Mitochondrial
Membrane Proteins--deficiency
Mice
Mice, Inbred C57BL
Mice, Knockout
Models, Neurological
Nerve Degeneration--genetics
Neurons--cytology
Protease Inhibitors--pharmacology
Proteasome Inhibitors
Proto-Oncogene Proteins--deficiency
Proto-Oncogene Proteins c-bcl-2--genetics
RNA, Small Interfering--genetics
Stress, Physiological
Tumor Suppressor Proteins--deficiency