Hypoxia and nickel inhibit histone demethylase JMJD1A and repress Spry2 expression in human bronchial epithelial BEAS-2B cells.

Chen, Haobin

Hypoxia and nickel inhibit histone demethylase JMJD1A and repress Spry2 expression in human bronchial epithelial BEAS-2B cells. [electronic resource] - Carcinogenesis Dec 2010 - 2136-44 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1460-2180

10.1093/carcin/bgq197 doi


Animals
Bronchi--drug effects
Bronchial Neoplasms--etiology
Carcinogens, Environmental--toxicity
Cell Hypoxia
Cell Proliferation--drug effects
Cells, Cultured
Down-Regulation
Extracellular Signal-Regulated MAP Kinases--metabolism
Humans
Hypoxia-Inducible Factor 1, alpha Subunit--physiology
Intracellular Signaling Peptides and Proteins--antagonists & inhibitors
Jumonji Domain-Containing Histone Demethylases--antagonists & inhibitors
Membrane Proteins
Mice
Nickel--toxicity
Respiratory Mucosa--cytology