SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776.
Duvick, Lisa
SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776. [electronic resource] - Neuron Sep 2010 - 929-35 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1097-4199
10.1016/j.neuron.2010.08.022 doi
Animals
Aspartic Acid--genetics
Ataxin-1
Ataxins
Calbindins
Cerebellum--pathology
Dendrites--metabolism
Disease Models, Animal
Gene Expression Regulation--genetics
Mice
Mice, Transgenic
Motor Activity--genetics
Mutation--genetics
Nerve Tissue Proteins--genetics
Neural Pathways--metabolism
Nuclear Proteins--genetics
Purkinje Cells--pathology
Rotarod Performance Test
S100 Calcium Binding Protein G--metabolism
Serine--genetics
Spinocerebellar Ataxias--genetics
Vesicular Glutamate Transport Protein 2--metabolism
SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776. [electronic resource] - Neuron Sep 2010 - 929-35 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1097-4199
10.1016/j.neuron.2010.08.022 doi
Animals
Aspartic Acid--genetics
Ataxin-1
Ataxins
Calbindins
Cerebellum--pathology
Dendrites--metabolism
Disease Models, Animal
Gene Expression Regulation--genetics
Mice
Mice, Transgenic
Motor Activity--genetics
Mutation--genetics
Nerve Tissue Proteins--genetics
Neural Pathways--metabolism
Nuclear Proteins--genetics
Purkinje Cells--pathology
Rotarod Performance Test
S100 Calcium Binding Protein G--metabolism
Serine--genetics
Spinocerebellar Ataxias--genetics
Vesicular Glutamate Transport Protein 2--metabolism