Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling.

Maurice, Pascal

Molecular organization and dynamics of the melatonin MT₁ receptor/RGS20/G(i) protein complex reveal asymmetry of receptor dimers for RGS and G(i) coupling. [electronic resource] - The EMBO journal Nov 2010 - 3646-59 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1460-2075

10.1038/emboj.2010.236 doi


Amino Acid Sequence
Cells, Cultured
Electrophysiology
Energy Transfer
G Protein-Coupled Inwardly-Rectifying Potassium Channels--metabolism
GTP-Binding Protein alpha Subunits, Gi-Go--chemistry
GTPase-Activating Proteins--chemistry
Guanosine 5'-O-(3-Thiotriphosphate)--metabolism
Humans
Immunoprecipitation
Kidney--cytology
Melatonin--metabolism
Membrane Proteins--chemistry
Molecular Sequence Data
Nerve Tissue Proteins--chemistry
Promoter Regions, Genetic--genetics
Protein Binding
Protein Conformation
Protein Multimerization
RGS Proteins
Receptor, Melatonin, MT1--chemistry
Signal Transduction