Abnormal modulation of cell protective systems in response to ischemic/reperfusion injury is important in the development of mouse sickle cell hepatopathy.

Siciliano, Angela

Abnormal modulation of cell protective systems in response to ischemic/reperfusion injury is important in the development of mouse sickle cell hepatopathy. [electronic resource] - Haematologica Jan 2011 - 24-32 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1592-8721

10.3324/haematol.2010.028506 doi


Anemia, Sickle Cell--etiology
Animals
Blotting, Western
Cells, Cultured
Cytoprotection
Female
HSP27 Heat-Shock Proteins--genetics
HSP70 Heat-Shock Proteins--genetics
Heme Oxygenase-1--genetics
Hepatocytes--cytology
Humans
Liver Diseases--etiology
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Mice, Transgenic
NF-kappa B--genetics
Nitric Oxide--metabolism
Nitric Oxide Synthase Type II--genetics
Nitric Oxide Synthase Type III--genetics
Peroxiredoxins--genetics
RNA, Messenger--genetics
Reperfusion Injury--complications
Reverse Transcriptase Polymerase Chain Reaction