Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.

Weeks, Amy M

Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity. [electronic resource] - Biochemistry Nov 2010 - 9269-79 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1520-4995

10.1021/bi101102u doi


Acetyl Coenzyme A--chemistry
Catalytic Domain
Crystallography, X-Ray
Escherichia coli
Fluorine--chemistry
Kinetics
Protein Binding
Protein Conformation
Streptomyces--enzymology
Substrate Specificity
Thermodynamics
Thiolester Hydrolases--chemistry
Water--chemistry