Structural insights into substrate specificity in variants of N-acetylneuraminic Acid lyase produced by directed evolution.

Campeotto, Ivan

Structural insights into substrate specificity in variants of N-acetylneuraminic Acid lyase produced by directed evolution. [electronic resource] - Journal of molecular biology Nov 2010 - 56-69 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1089-8638

10.1016/j.jmb.2010.08.008 doi


Amino Acid Substitution
Crystallography, X-Ray
Directed Molecular Evolution
Escherichia coli Proteins--chemistry
Models, Molecular
Mutant Proteins--chemistry
Mutation, Missense
Oxo-Acid-Lyases--chemistry
Protein Structure, Tertiary
Substrate Specificity