Akt inhibitors reduce glucose uptake independently of their effects on Akt.

Tan, Shi-Xiong

Akt inhibitors reduce glucose uptake independently of their effects on Akt. [electronic resource] - The Biochemical journal Nov 2010 - 191-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1470-8728

10.1042/BJ20100750 doi


3T3-L1 Cells
Adipocytes--cytology
Animals
Biological Transport--drug effects
Blotting, Western
Breast Neoplasms--metabolism
Cell Line, Tumor
Cell Membrane--metabolism
Erythrocytes--drug effects
Female
Glucose--pharmacokinetics
Glucose Transporter Type 4--metabolism
Humans
Mice
Phosphorylation--drug effects
Protein Kinase Inhibitors--pharmacology
Protein Transport--drug effects
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
Signal Transduction--drug effects