The effects of affinity and valency of an albumin-binding domain (ABD) on the half-life of a single-chain diabody-ABD fusion protein.

Hopp, Jonas

The effects of affinity and valency of an albumin-binding domain (ABD) on the half-life of a single-chain diabody-ABD fusion protein. [electronic resource] - Protein engineering, design & selection : PEDS Nov 2010 - 827-34 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1741-0134

10.1093/protein/gzq058 doi


Animals
Antibodies, Bispecific--genetics
CD3 Complex--immunology
Carcinoembryonic Antigen--immunology
Cell Line
Half-Life
Humans
Interleukin-2--immunology
Mice
Protein Binding
Recombinant Fusion Proteins--genetics
Serum Albumin--metabolism
T-Lymphocytes--immunology