Molecular mechanisms of biliary excretion of cefditoren and the effects of cefditoren on the expression levels of hepatic transporters.

Meng, Qiang

Molecular mechanisms of biliary excretion of cefditoren and the effects of cefditoren on the expression levels of hepatic transporters. [electronic resource] - Drug metabolism and pharmacokinetics 2010 - 320-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1880-0920

10.2133/dmpk.dmpk-09-rg-092 doi


ATP Binding Cassette Transporter, Subfamily G, Member 2
ATP-Binding Cassette Transporters--genetics
Animals
Anti-Bacterial Agents--pharmacokinetics
Bile--metabolism
Cephalosporins--pharmacokinetics
Drug Interactions
Liver--drug effects
Male
Novobiocin--pharmacology
Organic Anion Transporters, Sodium-Independent--genetics
Probenecid--pharmacology
RNA, Messenger--analysis
Rats
Rats, Wistar
Verapamil--pharmacology