Synergistic antitumor activity of sorafenib in combination with epidermal growth factor receptor inhibitors in colorectal and lung cancer cells.
Martinelli, Erika
Synergistic antitumor activity of sorafenib in combination with epidermal growth factor receptor inhibitors in colorectal and lung cancer cells. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Oct 2010 - 4990-5001 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1557-3265
10.1158/1078-0432.CCR-10-0923 doi
Animals
Antibodies, Monoclonal--administration & dosage
Antibodies, Monoclonal, Humanized
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Benzenesulfonates--administration & dosage
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Growth Processes--drug effects
Cell Line, Tumor
Cell Movement--drug effects
Cetuximab
Colorectal Neoplasms--drug therapy
Drug Synergism
ErbB Receptors--antagonists & inhibitors
Erlotinib Hydrochloride
Female
HCT116 Cells
HT29 Cells
Humans
Lung Neoplasms--drug therapy
Mice
Mice, Nude
Niacinamide--analogs & derivatives
Phenylurea Compounds
Protein Kinase Inhibitors--administration & dosage
Pyridines--administration & dosage
Quinazolines--administration & dosage
Receptors, Vascular Endothelial Growth Factor--biosynthesis
Signal Transduction--drug effects
Sorafenib
Xenograft Model Antitumor Assays
Synergistic antitumor activity of sorafenib in combination with epidermal growth factor receptor inhibitors in colorectal and lung cancer cells. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Oct 2010 - 4990-5001 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1557-3265
10.1158/1078-0432.CCR-10-0923 doi
Animals
Antibodies, Monoclonal--administration & dosage
Antibodies, Monoclonal, Humanized
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Benzenesulfonates--administration & dosage
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Growth Processes--drug effects
Cell Line, Tumor
Cell Movement--drug effects
Cetuximab
Colorectal Neoplasms--drug therapy
Drug Synergism
ErbB Receptors--antagonists & inhibitors
Erlotinib Hydrochloride
Female
HCT116 Cells
HT29 Cells
Humans
Lung Neoplasms--drug therapy
Mice
Mice, Nude
Niacinamide--analogs & derivatives
Phenylurea Compounds
Protein Kinase Inhibitors--administration & dosage
Pyridines--administration & dosage
Quinazolines--administration & dosage
Receptors, Vascular Endothelial Growth Factor--biosynthesis
Signal Transduction--drug effects
Sorafenib
Xenograft Model Antitumor Assays