Cortico-hippocampal hyperexcitability in synapsin I/II/III knockout mice: age-dependency and response to the antiepileptic drug levetiracetam.

Boido, D

Cortico-hippocampal hyperexcitability in synapsin I/II/III knockout mice: age-dependency and response to the antiepileptic drug levetiracetam. [electronic resource] - Neuroscience Nov 2010 - 268-83 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-7544

10.1016/j.neuroscience.2010.08.046 doi


4-Aminopyridine--pharmacology
Aging
Analysis of Variance
Animals
Anticonvulsants--pharmacology
Cerebral Cortex--drug effects
Disease Models, Animal
Drug Interactions
Electrodes
Epilepsy, Tonic-Clonic--genetics
Evoked Potentials--drug effects
Gene Expression Regulation--drug effects
Hippocampus--pathology
In Vitro Techniques
Levetiracetam
Membrane Glycoproteins--metabolism
Membrane Potentials--drug effects
Mice
Mice, Inbred C57BL
Mice, Knockout
Nerve Tissue Proteins--metabolism
Neurons--drug effects
Patch-Clamp Techniques
Piracetam--analogs & derivatives
Potassium Channel Blockers--pharmacology
Synapsins--deficiency
Synaptophysin--metabolism