Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1.

Crowley, Emily

Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1. [electronic resource] - The FEBS journal Oct 2010 - 3974-85 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1742-4658

10.1111/j.1742-4658.2010.07789.x doi


ATP Binding Cassette Transporter, Subfamily B--chemistry
ATP Binding Cassette Transporter, Subfamily B, Member 1--chemistry
Animals
Binding Sites
Catalytic Domain
Cysteine--chemistry
Energy Metabolism
Humans
Kinetics
Models, Molecular
Multidrug Resistance-Associated Proteins--chemistry
Mutation
Protein Conformation
Protein Isoforms--metabolism