A nonthiazolidinedione peroxisome proliferator-activated receptor α/γ dual agonist CG301360 alleviates insulin resistance and lipid dysregulation in db/db mice.

Jeong, Hyun Woo

A nonthiazolidinedione peroxisome proliferator-activated receptor α/γ dual agonist CG301360 alleviates insulin resistance and lipid dysregulation in db/db mice. [electronic resource] - Molecular pharmacology Nov 2010 - 877-85 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-0111

10.1124/mol.110.065748 doi


Adipocytes--drug effects
Animals
Cells, Cultured
Cyclooxygenase 2--biosynthesis
Cytokines--biosynthesis
Fatty Acids--metabolism
Gene Expression Regulation--drug effects
Glucose--metabolism
Insulin Resistance
Lipid Metabolism--drug effects
Macrophages--drug effects
Matrix Metalloproteinase 9--biosynthesis
Mice
Mice, Obese
Oxazoles--pharmacology
Oxidation-Reduction
PPAR alpha--agonists
PPAR delta--agonists
Pipecolic Acids--pharmacology
Stereoisomerism
Transcription, Genetic