Chiral 6-hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: novel antitumor DNA monoalkylating agents.

Soares, Maria I L

Chiral 6-hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: novel antitumor DNA monoalkylating agents. [electronic resource] - European journal of medicinal chemistry Oct 2010 - 4676-81 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1768-3254

10.1016/j.ejmech.2010.07.029 doi


Adenocarcinoma--drug therapy
Antineoplastic Agents, Alkylating--chemical synthesis
Breast Neoplasms--drug therapy
Cell Line, Tumor
Colorectal Neoplasms--drug therapy
DNA--metabolism
Drug Screening Assays, Antitumor
Female
Humans
Melanoma--drug therapy
Pyrroles--chemical synthesis
Thiazoles--chemical synthesis