SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells.

Fowler, Carla C

SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Sep 2010 - 3256-67 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1550-6606

10.4049/jimmunol.1001362 doi


Animals
CD8-Positive T-Lymphocytes--cytology
Cell Differentiation--genetics
Cell Line
Cell Survival--genetics
Cricetinae
Down-Regulation--genetics
Growth Inhibitors--deficiency
Immunologic Memory--genetics
Lymphocyte Depletion
Mice
Mice, Inbred C57BL
Mice, Knockout
Mice, Transgenic
Protein Tyrosine Phosphatase, Non-Receptor Type 6--deficiency
Stem Cells--cytology
T-Lymphocyte Subsets--cytology
T-Lymphocytes, Cytotoxic--cytology