The 4q12 amplicon in malignant peripheral nerve sheath tumors: consequences on gene expression and implications for sunitinib treatment.

Zietsch, Jan

The 4q12 amplicon in malignant peripheral nerve sheath tumors: consequences on gene expression and implications for sunitinib treatment. [electronic resource] - PloS one Jul 2010 - e11858 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0011858 doi


Antineoplastic Agents--therapeutic use
Apoptosis
Blotting, Western
Cell Line, Tumor
Humans
Immunohistochemistry
In Vitro Techniques
Indoles--therapeutic use
Nerve Sheath Neoplasms--drug therapy
Proto-Oncogene Proteins c-kit--genetics
Pyrroles--therapeutic use
Receptor, Platelet-Derived Growth Factor alpha--genetics
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--drug effects
Sunitinib
Vascular Endothelial Growth Factor A--genetics
Vascular Endothelial Growth Factor Receptor-2--genetics