An MEK-cofilin signalling module controls migration of human T cells in 3D but not 2D environments.

Klemke, Martin

An MEK-cofilin signalling module controls migration of human T cells in 3D but not 2D environments. [electronic resource] - The EMBO journal Sep 2010 - 2915-29 p. digital

Publication Type: Journal Article

1460-2075

10.1038/emboj.2010.153 doi


Actin Depolymerizing Factors--genetics
Actins--metabolism
Cell Movement
Cells, Cultured
Chemotaxis
Gene Knockdown Techniques
Humans
Lim Kinases--antagonists & inhibitors
Mitogen-Activated Protein Kinase Kinases--genetics
Models, Biological
Monomeric GTP-Binding Proteins--metabolism
Receptors, Chemokine--metabolism
Signal Transduction
T-Lymphocytes--physiology