Inhibition of ERK1/2 prevents neural and mesendodermal differentiation and promotes human embryonic stem cell self-renewal.

Na, Jie

Inhibition of ERK1/2 prevents neural and mesendodermal differentiation and promotes human embryonic stem cell self-renewal. [electronic resource] - Stem cell research Sep 2010 - 157-69 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1876-7753

10.1016/j.scr.2010.06.002 doi


Activins--pharmacology
Animals
Bone Morphogenetic Protein 4--pharmacology
Butadienes--pharmacology
Cell Differentiation
Embryonic Stem Cells--cytology
Fibroblast Growth Factor 2--pharmacology
Humans
Mesoderm--cytology
Mice
Mitogen-Activated Protein Kinase 1--antagonists & inhibitors
Mitogen-Activated Protein Kinase 3--antagonists & inhibitors
Neurons--cytology
Nitriles--pharmacology
Protein Kinase Inhibitors--pharmacology
Signal Transduction
Transforming Growth Factor beta--pharmacology