pfmdr1 amplification associated with clinical resistance to mefloquine in West Africa: implications for efficacy of artemisinin combination therapies.

Witkowski, Benoit

pfmdr1 amplification associated with clinical resistance to mefloquine in West Africa: implications for efficacy of artemisinin combination therapies. [electronic resource] - Journal of clinical microbiology Oct 2010 - 3797-9 p. digital

Publication Type: Case Reports; Journal Article

1098-660X

10.1128/JCM.01057-10 doi


Adult
Africa, Western
Artemisinins--pharmacology
Drug Resistance
Drug Therapy, Combination--methods
Gene Dosage
Humans
Inhibitory Concentration 50
Malaria, Falciparum--drug therapy
Male
Mefloquine--pharmacology
Multidrug Resistance-Associated Proteins--genetics
Treatment Failure