Determination of cisplatin 1,2-intrastrand guanine-guanine DNA adducts in human leukocytes by high-performance liquid chromatography coupled to inductively coupled plasma mass spectrometry.

Harrington, Chris F

Determination of cisplatin 1,2-intrastrand guanine-guanine DNA adducts in human leukocytes by high-performance liquid chromatography coupled to inductively coupled plasma mass spectrometry. [electronic resource] - Chemical research in toxicology Aug 2010 - 1313-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-5010

10.1021/tx100023c doi


Animals
Antineoplastic Agents--analysis
Cattle
Cell Line, Tumor
Cell Survival--drug effects
Chromatography, High Pressure Liquid
Cisplatin--analysis
DNA--chemistry
DNA Adducts--analysis
DNA, Neoplasm--drug effects
Drug Screening Assays, Antitumor
Guanine--chemistry
Humans
Leukocytes--cytology
Mass Spectrometry
Sensitivity and Specificity