Cathepsin B contributes to traumatic brain injury-induced cell death through a mitochondria-mediated apoptotic pathway.

Luo, Cheng-Liang

Cathepsin B contributes to traumatic brain injury-induced cell death through a mitochondria-mediated apoptotic pathway. [electronic resource] - Journal of neuroscience research Oct 2010 - 2847-58 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-4547

10.1002/jnr.22453 doi


Animals
Apoptosis--drug effects
Brain Injuries--drug therapy
Cathepsin B--antagonists & inhibitors
Chaperonin 60--metabolism
Cyclooxygenase 2--metabolism
Disease Models, Animal
Enzyme Inhibitors--pharmacology
Glial Fibrillary Acidic Protein--metabolism
Maze Learning--drug effects
Mice
Mitochondria--drug effects
Motor Activity--drug effects
Proto-Oncogene Proteins c-bcl-2--metabolism
Statistics, Nonparametric
Time Factors
Up-Regulation--drug effects