Enhanced induction of HIV-specific cytotoxic T lymphocytes by dendritic cell-targeted delivery of SOCS-1 siRNA.

Subramanya, Sandesh

Enhanced induction of HIV-specific cytotoxic T lymphocytes by dendritic cell-targeted delivery of SOCS-1 siRNA. [electronic resource] - Molecular therapy : the journal of the American Society of Gene Therapy Nov 2010 - 2028-37 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1525-0024

10.1038/mt.2010.148 doi


Apoptosis
Blotting, Western
Cell Proliferation
Cells, Cultured
Cytokines--metabolism
Dendritic Cells--immunology
Flow Cytometry
HIV--genetics
HIV Infections--immunology
HLA-A Antigens--immunology
HLA-A2 Antigen
Humans
Lipopolysaccharides--pharmacology
Myeloid Cells--drug effects
Peptide Fragments--pharmacology
RNA, Messenger--genetics
RNA, Small Interfering--genetics
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Suppressor of Cytokine Signaling 1 Protein
Suppressor of Cytokine Signaling Proteins--antagonists & inhibitors
T-Lymphocytes--drug effects
T-Lymphocytes, Cytotoxic--immunology