Poly(ADP-ribosyl)ation polymerases: mechanism and new target of anticancer therapy.

Heitz, Florian

Poly(ADP-ribosyl)ation polymerases: mechanism and new target of anticancer therapy. [electronic resource] - Expert review of anticancer therapy Jul 2010 - 1125-36 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

1744-8328

10.1586/era.10.53 doi


Aged
Antineoplastic Agents--pharmacology
Apoptosis Regulatory Proteins
BRCA1 Protein--deficiency
BRCA2 Protein--deficiency
Breast Neoplasms--drug therapy
Clinical Trials, Phase I as Topic
Clinical Trials, Phase II as Topic
DNA Breaks, Single-Stranded
DNA Repair
DNA, Neoplasm--metabolism
Drug Delivery Systems
Drug Resistance, Neoplasm
Enzyme Inhibitors--pharmacology
Female
Humans
Multicenter Studies as Topic
Neoplasm Proteins--antagonists & inhibitors
Ovarian Neoplasms--drug therapy
PTEN Phosphohydrolase--deficiency
Poly (ADP-Ribose) Polymerase-1
Poly Adenosine Diphosphate Ribose--metabolism
Poly(ADP-ribose) Polymerase Inhibitors
Poly(ADP-ribose) Polymerases--physiology