Genistein induces topoisomerase IIbeta- and proteasome-mediated DNA sequence rearrangements: Implications in infant leukemia.

Azarova, Anna M

Genistein induces topoisomerase IIbeta- and proteasome-mediated DNA sequence rearrangements: Implications in infant leukemia. [electronic resource] - Biochemical and biophysical research communications Aug 2010 - 66-71 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1090-2104

10.1016/j.bbrc.2010.07.043 doi


Animals
Cell Line, Tumor
DNA--drug effects
DNA Breaks, Double-Stranded
DNA Topoisomerases, Type I--metabolism
Genistein--adverse effects
Humans
Infant
Isoenzymes--metabolism
Leukemia, Myeloid, Acute--chemically induced
Mice
Proteasome Endopeptidase Complex--metabolism
Recombination, Genetic--drug effects