Therapeutic role of rifaximin in inflammatory bowel disease: clinical implication of human pregnane X receptor activation.

Cheng, Jie

Therapeutic role of rifaximin in inflammatory bowel disease: clinical implication of human pregnane X receptor activation. [electronic resource] - The Journal of pharmacology and experimental therapeutics Oct 2010 - 32-41 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Intramural

1521-0103

10.1124/jpet.110.170225 doi


Animals
Cell Line
Colon--metabolism
Dextran Sulfate
Gastrointestinal Agents--therapeutic use
Humans
Inflammatory Bowel Diseases--chemically induced
Leprostatic Agents--therapeutic use
Liver--metabolism
Luciferases--metabolism
Male
Metabolomics
Mice
Mice, Inbred C57BL
Mice, Knockout
Microsomes--metabolism
NF-kappa B--biosynthesis
Pregnane X Receptor
RNA, Messenger--biosynthesis
Receptors, Steroid--agonists
Rifampin--therapeutic use
Rifamycins--therapeutic use
Rifaximin
Stearoyl-CoA Desaturase--metabolism