Structure-based virtual screening, synthesis and SAR of novel inhibitors of hepatitis C virus NS5B polymerase.

Talele, Tanaji T

Structure-based virtual screening, synthesis and SAR of novel inhibitors of hepatitis C virus NS5B polymerase. [electronic resource] - Bioorganic & medicinal chemistry Jul 2010 - 4630-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1464-3391

10.1016/j.bmc.2010.05.030 doi


Allosteric Regulation
Antiviral Agents--chemical synthesis
Benzylidene Compounds--chemical synthesis
Binding Sites
Computer Simulation
Databases, Factual
Enzyme Inhibitors--chemical synthesis
Hepacivirus--enzymology
Rhodanine--chemical synthesis
Structure-Activity Relationship
Thiazoles--chemical synthesis
Viral Nonstructural Proteins--antagonists & inhibitors